9(E),11(E)-12-nitro Conjugated Linoleic Acid

• Catalog Number: orb1984976
• Category: Small Molecules
• Description: 9(E),11(E)-12-nitro Conjugated Linoleic Acid
• CAS Number: 1515620-30-0
• MW: 325.449
• SMILES: CCCCCC\C(=C/C=C/CCCCCCCC(O)=O)N(=O)=O
• Formula: C₁₈H₃₁NO₄
• Biological Activity: 9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.