You have no items in your shopping cart.
Cart summary
9-Decyn-1-ol
Catalog Number: orb1909241
| Catalog Number | orb1909241 |
|---|---|
| Category | Small Molecules |
| Description | 9-Decyn-1-ol is an alkyl/ether-based PROTAC linker used in synthesizing PROTACs, acting as a conjugation agent to combine GDC-0068 and Lenalidomide to form INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1]. |
| CAS Number | 17643-36-6 |
| Purity | 98.00% |
| MW | 154.25 |
| SMILES | C(CCCC#C)CCCCO |
| Formula | C10H18O |
| Biological Activity | 9-Decyn-1-ol is an alkyl/ether-based PROTAC linker suitable for synthesizing PROTACs. It serves as a conjugation agent to combine GDC-0068 and Lenalidomide, resulting in the formation of INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that operates through the PROTAC mechanism. It effectively inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
