7α,25-Dihydroxycholesterol

• Catalog Number: orb1089765
• Category: Small Molecules
• Description: 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells.
• CAS Number: [64907-22-8]
• MW: 418.652349
• SMILES: OC1C=C2C(C)(CCC(O)C2)C2C1C1C(C)(CC2)C(C(C)CCCC(O)(C)C)CC1
• Formula: C₂₇H₄₆O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.