α7 nAchR-JAK2-STAT3 agonist 1

• Catalog Number: orb1687725
• Category: Small Molecules
• Description: α7 nAchR-JAK2-STAT3 agonist 1
• CAS Number: 2108714-20-9
• Purity: 98%
• MW: 426.5
• SMILES: O(C(C)=O)C1=C(OC(C)=O)C=CC(CC[C@H](CCCCC2=CC=CC=C2)OC(C)=O)=C1
• Formula: C₂₅H₃₀O₆
• Biological Activity: α7 nAchR-JAK2-STAT3 agonist 1 is a potent α7 nAchR-JAK2-STAT3 agonist, with an IC 50 value of 0.32 μM for nitric oxide (NO). α7 nAchR-JAK2-STAT3 agonist 1 effectively suppresses the expression of iNOS, IL-1β, and IL-6 in murine RAW264.7 macrophages. α7 nAchR-JAK2-STAT3 agonist 1 can inhibit LPS-induced NO release, NF-κB activation and cytokine production. α7 nAchR-JAK2-STAT3 can be used for researching sepsis [1].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.