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Catalog Number | orb1710541 |
---|---|
Category | Small Molecules |
Description | 5-Iodo-indirubin-3'-monoxime |
CAS Number | 331467-03-9 |
MW | 403.17 |
SMILES | N(O)=C1C(NC=2C1=CC=CC2)=C3C=4C(NC3=O)=CC=C(I)C4 |
Formula | C16H10IN3O2 |
Biological Activity | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM). |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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