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Catalog Number | orb1694367 |
---|---|
Category | Small Molecules |
Description | 4-hydroxy Atorvastatin (calcium salt) |
CAS Number | 265989-44-4 |
Purity | 98% |
MW | 1191.393 |
SMILES | [CaH2].CC(C)c1c(C(=O)Nc2ccc(O)cc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccccc1.CC(C)c1c(C(=O)Nc2ccc(O)cc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccccc1 |
Formula | C66H72CaF2N4O12 |
Biological Activity | 4-hydroxy Atorvastatin is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |