You have no items in your shopping cart.
Cart summary
244cis
Catalog Number: orb2283561
| Catalog Number | orb2283561 |
|---|---|
| Category | Small Molecules |
| Description | 244cis, an ionizable cationic lipid incorporating a piperazine structure, facilitates the creation of lipid nanoparticles (LNPs). These LNPs, when formulated with 244cis and coated with an mRNA reporter gene, exhibit preferential accumulation in the lungs of mice, in contrast to those formulated with SM-102. Additionally, it leads to a reduction in the levels of serum chemokine (C-C motif) ligand 2 (CCL2) [1]. |
| CAS Number | 2956402-64-3 |
| Purity | 98.00% |
| MW | 970.54 |
| SMILES | C(CN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCCC(OC/C=C\CCCCCC)=O)N1CCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CC1 |
| Formula | C60H111N3O6 |
| Biological Activity | 244cis, an ionizable cationic lipid incorporating a piperazine structure, facilitates the creation of lipid nanoparticles (LNPs). These LNPs, when formulated with 244cis and coated with an mRNA reporter gene, exhibit preferential accumulation in the lungs of mice, in contrast to those formulated with SM-102. Additionally, it leads to a reduction in the levels of serum chemokine (C-C motif) ligand 2 (CCL2) [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
