2'-Fluoro-2'-Deoxyadenosine

• Catalog Number: orb1297913
• Category: Small Molecules
• Description: 2'-Fluoro-2'-Deoxyadenosine
• CAS Number: 64183-27-3
• Purity: 98%
• MW: 269.23
• SMILES: F[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)[C@H]1O
• Formula: C₁₀H₁₂FN₅O₃
• Biological Activity: 2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.