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Catalog Number | orb2283834 |
---|---|
Category | Small Molecules |
Description | 1,4-dideoxy-1,4-imino-D-Arabinitol hydrochloride |
CAS Number | 100991-92-2 |
MW | 169.61 |
SMILES | Cl.OC[C@H]1NC[C@@H](O)[C@@H]1O |
Formula | C5H12ClNO3 |
Biological Activity | 1,4-Dideoxy-1,4-imino-D-arabinitol (DAB) functions as an inhibitor of glycogen phosphorylase, a crucial enzyme in glycogenolysis, demonstrating the ability to hinder this process in isolated liver cells (IC50= 1.0 µM) and cerebral cortex and cerebellum homogenates (IC50s = 463 and 383 nM, respectively). Employed extensively in different animal models, DAB inhibits glycogenolysis within the liver and brain. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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