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Catalog Number | orb1704779 |
---|---|
Category | Small Molecules |
Description | 1,2,3,4,5,6-Hexabromocyclohexane |
CAS Number | 1837-91-8 |
Purity | 98% |
MW | 557.54 |
SMILES | BrC1C(Br)C(Br)C(Br)C(Br)C1Br |
Formula | C6H6Br6 |
Biological Activity | The compound effectively and directly inhibits JAK2 tyrosine kinase autophosphorylation and specifically inhibits ligand-dependent JAK2 activation. It has no cytotoxicity at 100 μM. A 16-hour treatment with compound (1 μM) decreases JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM eliminates nearly all JAK2 activity. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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