11R-VIVIT

• Catalog Number: orb1089487
• Category: Small Molecules
• Description: 11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.
• CAS Number: [592517-80-1]
• MW: 3573.15
• Formula: C₁₄₇H₂₅₉N₆₇O₃₆S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.